NR-CL(Nicotinamide Riboside Chloride) 98% CAS NO.23111-00-4

Taizhou Tyloo Biopharm Co.,Ltd  is located in the east coast of Zhejiang province, named Taizhou city, which is well known as raw chemicals production base at national level. It is a biopharm company focus on producing and sales of API,pharmaceutical intermediates,plant extracting ,aims at comprehensive supplying to the pharmaceutical and nutraceutical clients.Tyloo has a number of production bases,has established close cooperation with Chinese suppliers of API,Intermediates,plant extracting,intercommunicates resources and advantages,commits to the development of the international market and further.We would like to supply good quality goods with competitive price and better pre-sale after-sales service to clients on the basis of mutural benefit.

Tyloo’s r&d center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. Tyloo can provide different quantities of custom synthesis chemicals in lab, plant and industrial scale .Tyloo exported this product to many countries and regions at best price in china. if you are looking for the product’s supplier in china, Tyloo is your best choice.

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Vitamin derivatives Important application in preventing stem cell aging and maintaining stem cell function。Nicotinamide riboside (NR) is a pyridine-nucleoside form of vitamin B₃ that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.NR was first described in 1944 as a growth factor, termed Factor V, for Haemophilus influenza, a bacterium that lives in and depends on blood. Factor V, purified from blood was shown to exist in three forms: NAD+, NMN and NR. NR was the compound that led to the most rapid growth of this bacterium. Notably, H. influenza cannot grow on nicotinic acid, nicotinamide, tryptophan or aspartic acid, which were the previously known precursors of NAD+.In 2000, yeast Sir2 was shown to be an NAD+-dependent protein lysine deacetylase,which led several groups to probe yeast NAD+ metabolism for genes and enzymes that might regulate lifespan. Biosynthesis of NAD+ in yeast was thought to flow exclusively through NAMN (nicotinic acid mononucleotide）When NAD+ synthase (glutamine-hydrolysing) was deleted from yeast cells, NR permitted yeast cells to grow. Thus, these Dartmouth College investigators proceeded to clone yeast and human nicotinamide riboside kinases and demonstrate the conversion of NR to NMN by nicotinamide riboside kinases in vitro and in vivo. They also demonstrated that NR is a natural product, a little-noticed vitamin found in cow's milk

NR-CL is a salt form of NR,it's much more stable than NR, and it's could be used for further production.